utomation of 3 D reconstruction of neural tissue from large volume of onventional serial section transmission electron micrographs

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An Integrated Micro- and Macroarchitectural Analysis of the Drosophila Brain by Computer-Assisted Serial Section Electron Microscopy (2010, methodology): “The sheer size of the data sets has prompted the development of novel algorithms for the automatic segmentation and reconstruction of neural arbors [18].”
Convolutional Networks Can Learn to Generate Affinity Graphs for Image Segmentation (2010, background): “Most attempts at automation have involved hand-designed filtering architectures with little machine learning (Vasilevskiy & Siddiqi, 2002; Al-Kofahi et al., 2002; Jurrus et al., 2009; Mishchenko, 2009; Andres et al., 2008).”