Evolutionary relationships and structural mechanisms of AAA+ proteins.
By J. Erzberger, J. Berger. Annual Review of Biophysics and Biomolecular Structure, 2006
785 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/24dedaea06fb2d29afe9c550301561c3f196b8e7
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In Molecular Biology
Citations in the corpus
- Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system (2012, background): “As such, it can convert the energy of ATP hydrolysis to structurally remodel or unfold client protein”
- Stochastic mechano-chemical kinetics of molecular motors: A multidisciplinary enterprise from a physicist’s perspective (2012, background): “Its large head consists of 6 domains arranged in the form a ring that is a typical characteristics of the members of the AAA+ superfamily of ATPases [695, 696, 697, 698, 699, 700, 701, 702].”
- Crystal structures of asymmetric ClpX hexamers reveal nucleotide-dependent motions in a AAA+ protein-unfolding machine (2009, neutral): “In AAA+ enzymes, ATP/ ADP binds at the interface between the large and small AAA+ domains of one subunit and the large AAA+ domain of an adjacent subunit (Erzberger and Berger, 2006), creating six potential binding sites.”
- Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion (2020, neutral): “Some examples of similar fusions creating cavities exist in nature, such as AAA+-type molecular machines (33) or ATP-binding cassette (ABC) membrane transporters (34).”
- Reconstitution and structure of a plant NLR resistosome conferring immunity (2019, background): “Implications in the activation of other plant NLRs The present study supports the AvrAC-induced oligomerization of ZAR1-RKS1-PBL2UMP into the ZAR1 resistosome in the presence of dATP or ATP, further confirming oligomerization as a hallmark of AAA+ ATPases (9, 63).”