Assessment of protein assembly prediction in CASP12

By Aleix Lafita, Spencer E. Bliven, Andriy Kryshtafovych, Martino Bertoni, Bohdan Monastyrskyy, Jose M. Duarte, Torsten Schwede, Guido Capitani. 2018

71 citations recorded by the source corpus.

Subfields: Cell Biology, Materials Chemistry, Molecular Biology, Evaluation & Benchmarks, Computational Biology & Bioinformatics

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Anna Tramontano
2. Krzysztof Fidelis
3. John Moult
4. Andriy Kryshtafovych

In Materials Chemistry

1. Andriy Kryshtafovych
2. Torsten Schwede
3. Krzysztof Fidelis
4. Anna Tramontano
5. Yang Zhang
6. John Moult
7. Bohdan Monastyrskyy
8. Alessandro Barbato

In Molecular Biology

1. Torsten Schwede
2. Andriy Kryshtafovych
3. Krzysztof Fidelis
4. Yang Zhang
5. Anna Tramontano
6. John Moult
7. Bohdan Monastyrskyy
8. Gabriel Studer

In Evaluation & Benchmarks

1. Andriy Kryshtafovych
2. Torsten Schwede
3. Anna Tramontano
4. Krzysztof Fidelis
5. John Moult
6. Yang Zhang
7. Gabriel Studer
8. Lorenza Bordoli

In Computational Biology & Bioinformatics

1. Andriy Kryshtafovych
2. Torsten Schwede
3. Krzysztof Fidelis
4. Anna Tramontano
5. Yang Zhang
6. John Moult
7. Björn Wallner
8. Gabriel Studer

Citations in the corpus

• SWISS-MODEL: homology modelling of protein structures and complexes (2018, positive): “As highlighted by the introduction of the first assessment of protein assemblies in the recent CASP XII experiment (24), comparative modelling of protein complexes is receiving much attention and is expected to play a relevant role in the elucidation of the protein quaternary structure space.”
• Critical Assessment of Methods of Protein Structure Prediction (CASP) – Round XII (2017, methodology): “…was further strengthened in CASP12 by introducing a separate category in which the accuracy of the predicted complexes for all nonmonomeric targets was evaluated by a dedicated team of assessors, 36 and a subset of targets meeting CAPRI criteria was separately assessed in collaboration with CAPRI.”
• Blind prediction of homo- and hetero-protein complexes: The CASP13-CAPRI experiment (2019, neutral): “40-42 Here we present the results of the CASP13-CAPRI challenge, the third joint assembly prediction experiment with CASP, representing Round 46 of CAPRI.”
• Continuous Automated Model EvaluatiOn (CAMEO) complementing the critical assessment of structure prediction in CASP12 (2018, background): “Prediction of quaternary structures remains a challenge in structure prediction[55] as observed both in CAMEO and CASP12.”
• Assessment of the CASP14 Assembly Predictions (2021, methodology): “12 In CASP14, we had five targets (H1036, H1047, H1060, H1081, and T1099o), which were challenging to assess with the standard CASP metrics.”