Multiple wheat genomes reveal global variation in modern breeding

By Sean Walkowiak, Liangliang Gao, Cécile Monat, G. Haberer, Mulualem T. Kassa, J. Brinton, Ricardo H. Ramirez-Gonzalez, Markus C. Kolodziej, Emily E. Delorean, Dinushika Thambugala and 88 more. Nature, 2020

715 citations recorded by the source corpus.

Advances in genomics have expedited the improvement of several agriculturally important crops but similar efforts in wheat (Triticum spp.) have been more challenging. This is largely owing to the size and complexity of the wheat genome1, and the lack of genome-assembly data for multiple wheat lines2,3. Here we generated ten chromosome pseudomolecule and five scaffold assemblies of hexaploid wheat to explore the genomic diversity among wheat lines from global breeding programs. Comparative analysis revealed extensive structural rearrangements, introgressions from wild relatives and differences in gene content resulting from complex breeding histories aimed at improving adaptation to diverse environments, grain yield and quality, and resistance to stresses4,5. We provide examples outlining the utility of these genomes, including a detailed multi-genome-derived nucleotide-binding leucine-rich repeat protein repertoire involved in disease resistance and the characterization of Sm16, a gene associated with insect resistance. These genome assemblies will provide a basis for functional gene discovery and breeding to deliver the next generation of modern wheat cultivars. Comparison of multiple genome assemblies from wheat reveals extensive diversity that results from the complex breeding history of wheat and provides a basis for further potential improvements to this important food crop.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/2413629ae90b71efa64144d6f76d48faadb68681