In vivo imaging of neural activity

By Weijian Yang, Rafael Yuste. Nature Methods, 2017

398 citations recorded by the source corpus.

Since the introduction of calcium imaging to monitor neuronal activity with single-cell resolution, optical imaging methods have revolutionized neuroscience by enabling systematic recordings of neuronal circuits in living animals. The plethora of methods for functional neural imaging can be daunting to the nonexpert to navigate. Here we review advanced microscopy techniques for in vivo functional imaging and offer guidelines for which technologies are best suited for particular applications.

Subfields: Biophysics, Cellular and Molecular Neuroscience

View Paper: https://www.semanticscholar.org/paper/23f77b8bce51e1db9e894b39eebed8a834b91b4a

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Citations in the corpus

• Tracking the Same Neurons across Multiple Days in Ca2+ Imaging Data (2017, background): “…in data from one-photon Ca2+ imaging, in comparison to two-photon imaging, due to light scattering and lack of optical sectioning (Wilt et al., 2009; Yang and Yuste, 2017), both of which increase the crosstalk between the signals of neighboring neurons in the two-dimensional field of view (FOV).”