Nanoparticle characterization: State of the art, challenges, and emerging technologies

By E. Cho, H. Holback, Karen C. Liu, Sara A. Abouelmagd, Joonyoung Park, Y. Yeo. Molecular Pharmaceutics, 2013

339 citations recorded by the source corpus.

Nanoparticles have received enormous attention as a promising tool to enhance target-specific drug delivery and diagnosis. Various in vitro and in vivo techniques are used to characterize a new system and predict its clinical efficacy. These techniques enable efficient comparison across nanoparticles and facilitate a product optimization process. On the other hand, we recognize their limitations as a prediction tool, which owe to inadequate applications and overly simplified test conditions. This article provides a critical review of in vitro and in vivo techniques currently used for evaluation of nanoparticles and introduces emerging techniques and models that may be used complementarily.

Subfields: Biomaterials, Molecular Biology, Pharmaceutical Science

View Paper: https://www.semanticscholar.org/paper/238eb40ebdbee5a5cd4380b44d40e2fdb9f8d313

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Citations in the corpus

A review on the classification, characterisation, synthesis of nanoparticles and their application (2017, methodology): “Some methods are modified to achieve process specific nanoparticles to increase their optical, mechanical, physical and chemical properties [3].”
Engineered nanoparticles interacting with cells: size matters (2014, background): “However, the method suffers from low sensitivity toward small particles and possible interference from light-absorbing species [20].”