Quantitative phase imaging via Fourier ptychographic microscopy

By Xiaoze Ou, Roarke Horstmeyer, Changhuei Yang, Guoan Zheng. Optics Letters, 2013

326 citations recorded by the source corpus.

Fourier ptychographic microscopy (FPM) is a recently developed imaging modality that uses angularly varying illumination to extend a system’s performance beyond the limit defined by its optical components. The FPM technique applies a novel phase-retrieval procedure to achieve resolution enhancement and complex image recovery. In this Letter, we compare FPM data to theoretical prediction and phase-shifting digital holography measurement to show that its acquired phase maps are quantitative and artifact-free. We additionally explore the relationship between the achievable spatial and optical thickness resolution offered by a reconstructed FPM phase image. We conclude by demonstrating enhanced visualization and the collection of otherwise unobservable sample information using FPM’s quantitative phase.

Subfields: Atomic and Molecular Physics, and Optics, Radiation, Structural Biology

View Paper: https://www.semanticscholar.org/paper/235cfb1e4c9299b3350bc9ba64e7a632e5d62450

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Atomic and Molecular Physics, and Optics

1. Lei Tian
2. Jingshan Zhong
3. Li-Hao Yeh
4. Laura Waller

In Radiation

1. Jingshan Zhong
2. Li-Hao Yeh
3. Lei Tian
4. Laura Waller

In Structural Biology

1. Laura Waller
2. Lei Tian

Citations in the corpus

• Computational illumination for high-speed in vitro Fourier ptychographic microscopy (2015, methodology): “Previous work in FPM uses a low-resolution intensity image as the initial guess [7,15,16,31].”