Generation of protein lattices by fusing proteins with matching rotational symmetry.

222 citations recorded by the source corpus.

Citations in the corpus

Self-assembling protein nanoparticles in the design of vaccines (2015, unknown): “The Noble team used proteins with higher symmetry, allowing design of fusions with two or more connections, generating regular molecular arrays that formed protein lattices, but not closed nanohedral particles [114].”
Generation of ordered protein assemblies using rigid three-body fusion (2020, unknown): “The genetic fusion route was originally demonstrated with the creation of a tetrahedral protein nanocage and fiber (5) and has since been used to generate two-dimensional (2D) layers (6), a porous cube (7), additional tetrahedra (8, 9), octahedra (10), and icosahedra (11, 12).”
Design of a hyperstable 60-subunit protein icosahedron (2016, unknown): “Protein assemblies have been engineered using metals 9,10 , disulfide bonds 11–14 , genetic fusions 12,15–17 , and ideal helix-helix interactions 11,13,16 , but these approaches have generally yielded polydisperse or unanticipated products.”