The role of complement in inflammatory diseases from behind the scenes into the spotlight.
By M. Markiewski, John D Lambris. American Journal of Pathology, 2007
734 citations recorded by the source corpus.
Subfields: Immunology, Nephrology, Physiology
View Paper: https://www.semanticscholar.org/paper/22f00767188968a4a13037cf80200c11d3601b65
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In Immunology
- S. Ostrand-Rosenberg
- A. Klos
- P. Sinha
- J. Köhl
- Edimara S. Reis
- Rahasson R. Ager
- Kay O. Johswich
- A. Tenner
Citations in the corpus
- The Pivotal Role of the Complement System in Aging and Age-related Macular Degeneration: Hypothesis Re-visited (2009, positive): “…innate immune system, the complement system provides for opsonization and lysis of microorganisms, removal of foreign particles and dead cells, recruitment and activation of inflammatory cells, regulation of antibody production, and elimination of immune complexes (Markiewski and Lambris, 2007).”
- Myeloid-Derived Suppressor Cells: Linking Inflammation and Cancer (2009, background): “C5a, also known as anaphylatoxin, and C3a have inherent inflammatory activity, are chemoattractants, and localize to endothelial cells within solid tumors (97, 98).”
- Modulation of the anti-tumor immune response by complement (2008, background): “Another potential participant in the response to cancer is the complement system, which is essential in inflammation and in the innate immune response to infectio”
- Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome (2009, background): “Although the complement system plays an important role in protecting the host against infectious diseases and aiding in the repair of damaged tissue, unregulated or inappropriate activation of the complement cascade can in itself lead to tissue injury (14).”
- Role of Antioxidants and Natural Products in Inflammation (2016, background): “Even though an inflammatory response can happen in any injurious stimulus, the characteristic of this process is the reaction of vascularized connective tissue [3] .”
- The Role of the Anaphylatoxins in Health and Disease (2009, positive): “, 2002a), serine proteases of the clotting and the fibrinolysis system (Huber-Lang et al., 2006; Markiewski and Lambris, 2007) and several pathogens (see Section 3.”