Machine learning for metagenomics: methods and tools

By Hayssam Soueidan, Macha Nikolski. 2015

66 citations recorded by the source corpus.

Owing to the complexity and variability of metagenomic studies, modern machine learning approaches have seen increased usage to answer a variety of question encompassing the full range of metagenomic NGS data analysis. We review here the contribution of machine learning techniques for the field of metagenomics, by presenting known successful approaches in a unified framework. This review focuses on five important metagenomic problems: OTU-clustering, binning, taxonomic profling and assignment, comparative metagenomics and gene prediction. For each of these problems, we identify the most prominent methods, summarize the machine learning approaches used and put them into perspective of similar methods. We conclude our review looking further ahead at the challenge posed by the analysis of interactions within microbial communities and different environments, in a field one could call "integrative metagenomics".

Subfields: Ecology, Molecular Biology

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In Ecology

  1. Jinbo Xu
  2. Gail L. Rosen

In Molecular Biology

  1. Casey S. Greene
  2. Yifan Peng
  3. Brett K. Beaulieu-Jones
  4. G. Way
  5. Amr M. Alexandari
  6. Zhiyong Lu
  7. Avanti Shrikumar
  8. S. Joshua Swamidass

Citations in the corpus