Regression of microalbuminuria in type 1 diabetes.

By B. Perkins, Linda H. Ficociello, K. Silva, D. Finkelstein, J. Warram, A. Krolewski. New England Journal of Medicine, 2003

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Pathogenesis of Diabetic Nephropathy (2004, positive): “When detected in early stages, a more recent study has shown that regression of microalbuminuria is feasible, and this correlates with preservation of renal function [33].”
An updated overview of diabetic nephropathy: Diagnosis, prognosis, treatment goals and latest guidelines (2020, background): “Perkins et al reported regression of albuminuria in 386 people with T1DM and moderate (A2) albuminuria who were evaluated over a 6-year follow-up period.(5) After 6 years, the cumulative incidence of progression to severe (A3) albuminuria was 19% (95% CI 14-23%).”
Diabetic Kidney Disease: A Report From an ADA Consensus Conference (2014, neutral): “0%, systolic BP (SBP),115 mmHg, and serum lipids in target (total cholesterol ,198 mg/dL and triglycerides ,145 mg/dL) than those who did not meet these targets (19).”
Care of children and adolescents with type 1 diabetes: a statement of the American Diabetes Association. (2005, positive): “Microalbuminuria is a sign of early nephropathy at a stage when nephropathy may be reversible with careful glycemic and blood pressure contro l (2,133,134).”
Diabetic Nephropathy: Challenges in Pathogenesis, Diagnosis, and Treatment (2021, background): “At the time of microalbuminuria, there has been advanced glomerulopathy [8, 9]; on the other hand, a large number of patients with microalbuminuria can regress to normoalbuminuria [10].”