Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution

By Patrick Cramer, D. Bushnell, R. Kornberg. Science, 2001

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Phosphorylation and functions of the RNA polymerase II CTD. (2006, background): “…fully phosphorylated CTD is likely to extend multiple diameters out from the globular portion of RNAPII (a stretched-out yeast CTD would extend ∼650 Å [Meinhart et al. 2005], and the mammalian CTD is twice as long; the diameter of the globular portion of the enzyme is ∼150 Å [Cramer et al. 2001]).”
The General Transcription Machinery and General Cofactors (2006, methodology): “Comparison of the structures between the 10-subunit free core enzyme and a transcribing elongation complex containing the same core enzyme in complex with 9 base pairs of an RNA-DNA hybrid within a partially unwound DNA duplex has revealed detailed information regarding subunit-subunit and protein-n”
ELM server: a new resource for investigating short functional sites in modular eukaryotic proteins (2003, background): “yeast RNA polymerase II (12) illustrates this point.”
Structures of RNA polymerase II complexes with Bye1, a chromatin-binding PHF3/DIDO homologue (2013, background): “The views correspond to the side and front views of Pol II (46) and are related by a 90° rotation around a vertical axis.”
Plant nuclear RNA polymerase IV mediates siRNA and DNA methylation-dependent heterochromatin formation. (2005, background): “Archambault, J., and Friesen, J.D. (1993).”