Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair.

By Xinping Zhang, Edward M. Schwarz, Donald A. Young, J. Puzas, R. Rosier, R. O’Keefe. Journal of Clinical Investigation, 2002

746 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/21deae1522032f9a72732da2e4065f601c9ffd27

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1. R. Landewé
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Citations in the corpus

• Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial. (2005, background): “COX-2 is relevant in bone formation: both COX-2– knockout mice and mice treated with COX-2–inhibiting drugs showed reduced callus formation after a fracture, which is attributable to suppression of osteoblasts (22).”