Adverse Impact of Bleeding on Prognosis in Patients With Acute Coronary Syndromes

By J. Eikelboom, S. Mehta, Sonia S Anand, Changchun Xie, K. Fox, S. Yusuf. Circulation, 2006

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Impact of major bleeding on 30-day mortality and clinical outcomes in patients with acute coronary syndromes: an analysis from the ACUITY Trial. (2007, background): “(5), which reported major leeding in 2.”
Radial versus femoral access for coronary angiography or intervention and the impact on major bleeding and ischemic events: a systematic review and meta-analysis of randomized trials. (2009, background): “We restricted our analysis to major bleeding because of the increasing evidence relating major bleeding with mortality and recurrent ischemic events and found a similar benefit with radial access.(3,4) Several large observational studies have demonstrated that radial access reduces major bleeding co”