Vertex models of epithelial morphogenesis.

By A. Fletcher, M. Osterfield, Ruth E. Baker, Stanislav Y. Shvartsman. Biophysical Journal, 2014

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A Review of Cell-Based Computational Modeling in Cancer Biology (2019, methodology): “Vertex-based methods (eg, Fletcher et al 28 ) model cells as polygons (2D) or polyhedra (3D) and compute the forces that act on their vertices; they are particularly useful for modeling con ﬂ uent tissues.”