Apixaban Metabolism and Pharmacokinetics after Oral Administration to Humans

By Nirmala Raghavan, C. Frost, Zhigang Yu, K. He, Haiying Zhang, W. Humphreys, D. Pinto, Shiang-Yuan Chen, S. Bonacorsi, P. Wong and 1 more. Drug Metabolism And Disposition, 2009

663 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine

View Paper: https://www.semanticscholar.org/paper/20644a62004e752b2f636b02a9980a02a6cef3dd

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. E. Vandermeuelen
2. S. Kopp
3. T. Horlocker
4. W. Gogarten
5. L. Leffert
6. H. Benzon

Citations in the corpus

• Regional Anesthesia in the Patient Receiving Antithrombotic or Thrombolytic Therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Fourth Edition) (2018, background): “Approximately 27% of the clearance is renal; the remainder will undergo hepatic or biliary transformation prior to being eliminated via the gut.(121,135) The terminal elimination half-life in healthy patients is 10 to 15 hours and is onlymarginally influenced by the renal function, with half-life in”