Organic osmolytes as compatible, metabolic and counteracting cytoprotectants in high osmolarity and other stresses

By P. Yancey. Journal of Experimental Biology, 2005

1,762 citations recorded by the source corpus.

Subfields: Ecology, Evolution, Behavior and Systematics, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/1fb5babc32dfbe1ad6a42f24589a16751176a664

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Citations in the corpus

High-throughput production of human proteins for crystallization: The SGC experience (2010, background): “5 M trimethylamine N-oxide (TMAO) (Yancey, 2005), or a mixture of arginine and glutamate (0.”
Improvement of salinity stress tolerance in rice: Challenges and opportunities (2016, background): “In an environment that has osmotic concentration changes, these osmolytes can be up- or down-regulated to prevent osmotic shrinkage in many species [26].”
Research note: Salinity tolerance of Arctic kelps from Spitsbergen (2007, background): “…mannitol is one of the most potent organic osmolytes in many other organisms, which not only balances salinity stress, but also can act as antioxidant, and rapidly available respiratory substrate (energy supply for a maintenance metabolism under stress and for repair processes) (Yancey 2005).”
Balance of enthalpy and entropy in depletion forces (2013, background): “We review the available models for these thermodynamic mechanisms, and comment on the need for new models that would be able to explain the full range of observed depletion forces.”
Abiotic Stress in Plants and Metabolic Responses (2013, background): “Scavenging of reactive oxygen species (ROS) to restore redox metabolism, preservation of cellular turgor by restitution of osmotic balance, and associated protection and stabilization of proteins and cellular structures are among the multiple protective functions of compatible osmoprotectants during”
Elucidating the molecular mechanisms mediating plant salt-stress responses. (2018, background): “…of salt-mediated osmotic stress pathways (both shortterm and long-term) induces the biosynthesis and accumulation of compatible osmolytes to reduce the cell osmotic potential and stabilize proteins and cellular structures; this is a primary adaptive strategy (Yancey et al., 1982; Blumwald, 2003).”
ECOPHYSIOLOGICAL PERFORMANCE OF THE AEROTERRESTRIAL GREEN ALGA KLEBSORMIDIUM CRENULATUM (CHAROPHYCEAE, STREPTOPHYTA) ISOLATED FROM AN ALPINE SOIL CRUST WITH AN EMPHASIS ON DESICCATION STRESS 1 (2010, background): “…layers, ‘‘self-protection’’ by cell aggregates, or biosynthesis ⁄ accumulation of ‘‘water-holding’’ organic molecules (e.g., compatibles solutes) also affect the ability of algal cells to retain cellular water (Yancey 2005, Flechtner 2007, Karsten et al. 2007, Rindi 2007, Gustavs et al. 2010).”
Physiological mechanisms of seasonal and rapid cold‐hardening in insects (2013, background): “The functions of these compounds include stabilizing membranes and proteins, enhancing supercooling capacity, and preventing osmotic damage to cells (Yancey, 2005).”
Proline Metabolism and Its Implications for Plant-Environment Interaction (2010, background): “Protection of cellular structure during dehydration: Proline has properties (highly soluble, zwitterionic) observed in compatible solutes that accumulate in organisms as diverse as bacteria and deep sea animals (Yancey et al., 1982; Yancey, 2005).”
Role of sugars, amino acids and organic acids in improving plant abiotic stress tolerance (2020, background): “Role of sugars in protein stabilization has also been studied in detail (Crow et al., 1987; Yancey, 2005).”