Reducing safety-related drug attrition: the use of in vitro pharmacological profiling

By J. Bowes, A. J. Brown, J. Hamon, W. Jarolimek, A. Sridhar, Gareth J Waldron, S. Whitebread. Nature reviews. Drug discovery, 2012

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Lysosomes as a therapeutic target (2019, background): “In this regard, the tremendous work in recent years to establish international guidelines for standardizing research in autophagy -and, in particular, to propose relevant methodologies for monitoring autophagy that are accepted by the whole community -is unique 231, 232 .”
Open Targets Platform: supporting systematic drug–target identification and prioritisation (2020, neutral): “We also provide information on target safety where available, including known side effects (28,29), safety risk information (30,31) and non-clinical experimental toxicity (32,33).”