Duloxetine vs. placebo in patients with painful diabetic neuropathy

By D. Goldstein, Yili Lu, M. Detke, Thomas C. Lee, S. Iyengar. Pain, 2005

839 citations recorded by the source corpus.

Subfields: Neurology, Oncology, Physiology

View Paper: https://www.semanticscholar.org/paper/1f890d7508602ee2d616b9a91240346d45dfc525

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. Alec B. O’Connor
2. N. Finnerup
3. T. S. Jensen

In Physiology

1. Alec B. O’Connor
2. T. S. Jensen
3. N. Finnerup
4. S. Sindrup
5. Clifford J. Woolf

Citations in the corpus

• The evidence for pharmacological treatment of neuropathic pain (2010, background): “The serotonin noradrenaline reuptake inhibitors (SNRIs) duloxetine and venlafaxine have a well-documented efficacy in painful poly-neuropathy [40,74,80,95,114], but venlafaxine failed to relieve postmastectomy in a low dose [102] and neuropathic pain of different etiologies in one small study [123](”
• Effect of duloxetine on pain, function, and quality of life among patients with chemotherapy-induced painful peripheral neuropathy: a randomized clinical trial (2013, background): “Several phase 3 studies show that duloxetine is an effective treatment for painful diabetic neuropathy.(12-15) Based on these trials, our hypothesis was that duloxetine would ameliorate chemotherapy-induced peripheral neuropathic pain as well.”
• Algorithm for neuropathic pain treatment: An evidence based proposal (2005, neutral): “It has demonstrated significantly greater pain relief compared with placebo in three RCTs in patients with painful DPN [38,82,128], but it has not been studied in other types of NP.”
• Recommendations for the management of herpes zoster. (2007, background): “strated to have efficacy in patients with diabetic polyneuropathy [163, 164].”
• Pharmacologic management of neuropathic pain: Evidence‐based recommendations (2007, positive): “It has demonstrated significantly greater pain relief compared with placebo in three RCTs in patients with painful DPN [38,82,128], but it has not been studied in other types of NP.”