Principles of Cryobiology

By P. Mazur. 2004

300 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Cryopreservation of Phytodiversity: A Critical Appraisal of Theory & Practice (2008, background): “The underlying principle that determines cell survival during cryopreservation was first described by Peter Mazur (see review, Mazur, 2004) and in his hypothesis, cooling rate and cryoprotectant permeability are key parameters.”
The thermal limits to life on Earth (2014, background): “In addition, intracellular ice can form when the cooling rate is sufficiently high that the cell cannot maintain osmotic equilibrium with the environment (Mazur 2004).”
Physiology of Desiccation-Sensitive (Recalcitrant) Seeds and the Implications for Cryopreservation (2013, background): “…and high electrolyte concentrations associated with dehydration may kill the cells; if the rate is too high, water may not be able to leave the cells fast enough to concentrate the solution, the cells become further supercooled, and intracellular ice formation is likely (reviewed by Mazur 2004).”