Cloning, mapping, and characterization of a human homologue of the yeast longevity assurance gene LAG1.

By H. Pan, W. Qin, K. Huo, D. Wan, Yao Yu, Zhigang Xu, Q. Hu, Kerong T. Gu, Xiaomei Zhou, Huiqiu Jiang and 4 more. 2001

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Citations in the corpus

Primary functional identification of gene TMSG-1 (2003, background): “V-ATPase [ 2 ] , but the role it played was not clear.”
Manipulation of thyroid status and/or GH injection alters hepatic gene expression in the juvenile chicken (2007, background): “We discovered the chicken homolog of the yeast longevity-assurance gene (LASS2) , a T 3 -depressed gene in chickens, which seems to regulate hepatocyte growth in humans (Pan et al., 2001).”
Differential expression of (dihydro)ceramide synthases in mouse brain: oligodendrocyte-specific expression of CerS2/Lass2 (2008, unknown): “Expression of CerS has been examined by Northern blot analysis and RT-PCR (Riebeling et al. 2003; Pan et al. 2001; Mizutani et al. 2005; Xu et al. 2005).”
Multiple New Loci Associated with Kidney Function and Chronic Kidney Disease: The CKDGen consortium (2010, unknown): “1q21 LASS2 LAG1 homolog, ceramide synthase 2 (LASS2) is highly expressed in the kidney and may be involved in cell growth.(46) A non-synonymous coding SNP in LASS2, rs267738 (E115A), was in perfect LD with the lead SNP in the region and of predicted damaging function.”
Molecular Cloning, Characterisation and Tissue-specific Expression of Human LAG3, a Member of the Novel Lag1 Protein Family (2003, background): “However, the sequence of LASS2 is only 1977 bp (Pan et al., 2001).”
Human MicroRNA Targets (2004, background): “…(1) CNOT7, a gene expressed in colorectal cell lines and primary tumors (Flanagan et al. 2003) (miR-15a); (2) LASS2, a tumor metastasis suppressor (Pan et al. 2001) (miR- 15b); (3) ING4, a homolog of the tumor suppressor p33 ING1b, which stimulates cell cycle arrest, repair, and apoptosis…”