Intragenic DNA methylation prevents spurious transcription initiation

By F. Neri, S. Rapelli, A. Křepelová, Danny Incarnato, C. Parlato, Giulia Basile, M. Maldotti, F. Anselmi, S. Oliviero. Nature, 2017

658 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/1e92f02718723d76aae589d66f60a1d9a01188d5

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In Molecular Biology

1. B. O’Malley
2. Alexander Meissner
3. Nina Bailly
4. Alexandra L. Mattei
5. Leah A. Gates
6. C. Foulds
7. S. Yamanaka

Citations in the corpus

• DNA methylation: a historical perspective. (2022, positive): “(C) Li et al. assayed genomic 5-methylcytosine (5mC) levels by methylationsensitive HpaII digestion in wild type (wt) (+/+) andDnmt1mutant (+/–, –/–) embryonic stem cells (ESCs) and E10.”
• Histone Marks in the 'Driver's Seat': Functional Roles in Steering the Transcription Cycle. (2017, background): “Extensive work by the Oliviero laboratory demonstrated that DNMT3b co-localizes with H3K36me3, and knockdown of either DNMT3b or SETD2 increases intragenic transcription through the creation of new TSSs [73].”