Sample Design and Cohort Selection in the Hispanic Community Health Study/Study of Latinos

By L. LaVange, William D. Kalsbeek, P. Sorlie, Larissa M. Avilés-Santa, R. Kaplan, J. Barnhart, Kiang Liu, A. Giachello, David J Lee, J. Ryan and 2 more. Annals of Epidemiology, 2010

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PURPOSE The Hispanic Community Health Study (HCHS)/Study of Latinos (SOL) is a multi-center, community based cohort study of Hispanic/Latino adults in the United States. A diverse participant sample is required that is both representative of the target population and likely to remain engaged throughout follow-up. The choice of sample design, its rationale, and benefits and challenges of design decisions are described in this paper. METHODS The study design calls for recruitment and follow-up of a cohort of 16,000 Hispanics/Latinos aged 18-74 years, with 62.5% (10,000) over 44 years of age and adequate subgroup sample sizes to support inference by Hispanic/Latino background. Participants are recruited in community areas surrounding four field centers in the Bronx, Chicago, Miami, and San Diego. A two-stage area probability sample of households is selected with stratification and over-sampling incorporated at each stage to provide a broadly diverse sample, offer efficiencies in field operations, and ensure that the target age distribution is obtained. CONCLUSIONS Embedding probability sampling within this traditional, multi-site cohort study design enables competing research objectives to be met. However, the use of probability sampling requires developing solutions to some unique challenges in both sample selection and recruitment, as described here.

Subfields: Sociology and Political Science, Statistics and Probability

View Paper: https://www.semanticscholar.org/paper/1db31be5aa8aaa9bc96d4cc1b3656fd4be414cfb

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