Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?

By Dean G. Brown, Jonas Boström. Journal of Medicinal Chemistry, 2016

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Organic synthesis in a modular robotic system driven by a chemical programming language (2019, methodology): “The carboxylic acid ( 14 ) was thoroughly dried by flowing argon through the filter cake while at the same time heating the filtration module to 60°C, after which acid chloride formed with thionyl chloride in dichloro-methane.”