End group removal and modification of RAFT polymers
By H. Willcock, R. O’Reilly. 2010
459 citations recorded by the source corpus.
This paper describes both well-established routes and recent advances in the end group modification of polymers synthesised by reversible addition–fragmentation chain transfer (RAFT) polymerisation. The lability of the thiocarbonylthio group, which facilitates the RAFT mechanism, allows for ready post-polymerisation functionalisation of RAFT polymers by a number of techniques. In particular, end group thermolysis, radical induced reduction, hetero-Diels–Alder reactions and reaction with nucleophiles are discussed as are the applications and limitations of each method. The versatility of RAFT as a polymerisation tool for the synthesis of polymers with functional end groups for a range of applications is demonstrated.
Subfields: Molecular Biology, Organic Chemistry
View Paper: https://www.semanticscholar.org/paper/1d5fa4ed6e6978d4776cb8dff8a0936031e5265e
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In Molecular Biology
In Organic Chemistry
Citations in the corpus
- One-pot multi-step reactions based on thiolactone chemistry: A powerful synthetic tool in polymer science (2015, background): “Indeed, the aminolysis of the RAFT end group is a popular route towards (semi-) telechelics bearing a chain end thiol [53], which can subsequently be employed as a nucleophile in a thiol-bromo conjugation [54] and Michael addition [55] or as a thiyl radical in thiol-ene [55c,56] and thiol-yne [57] c”