Primary care-led weight management for remission of type 2 diabetes (DiRECT): an open-label, cluster-randomised trial.

By M. Lean, W. Leslie, A. Barnes, Naomi Brosnahan, G. Thom, Louise McCombie, C. Peters, S. Zhyzhneuskaya, A. Al-Mrabeh, K. Hollingsworth and 15 more. The Lancet, 2017

1,688 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Pharmacy, Surgery

View Paper: https://www.semanticscholar.org/paper/1c6fc2925c1eab869c6f9f8722d06bb35f10625b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

In Pharmacy

I. Neeland

In Surgery

Citations in the corpus

Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association (2023, background): “…loss and significant lifestyle changes, which have been associated with reductions in adipose tissue and improvements in glucose tolerance (stage 1) 142,143 ; remission of diabetes, 142 hypertension, 144 hyperlipidemia, 143 and MetS, as well as improvements in kidney function 145 (stage 2); and…”
Nutrition Therapy for Adults With Diabetes or Prediabetes: A Consensus Report (2019, background): “Previous recommendations of weight loss of 5% or $7% for people with overweight or obesity are based on the threshold needed for therapeutic advantages; however, weight loss targeted at$15%, when such can feasibly and safely be accomplished, is associated with even better outcomes in type 2 diabetes”
Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers (2019, background): “Better outcomes were reported for DSMES interventions that were over 10 h in total duration (18), included ongoing support (12,27), were culturally (28,29) and age”
2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2021. (2020, background): “Certain medications, such as glucocorticoids, thiazide diuretics, some HIV medications (23), and atypical antipsychotics (66), are known to increase the risk of diabetes and should be considered when”
5. Lifestyle Management: Standards of Medical Care in Diabetes—2019 (2018, background): “, 15%) may be appropriate to maximize benefit depending on need, feasibility, and safety (73).”
Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) (2022, neutral): “In the whole study population, remission directly varied with degree of weight loss [88].”
2. Classification and Diagnosis of Diabetes: Standards of Medical Care in Diabetes-2022. (2021, background): “Certain medications, such as glucocorticoids, thiazide diuretics, some HIV medications (30), and atypical antipsychotics (90), are known to increase the risk of diabetes and should be considered when deciding whether to screen.”