Cardiovascular and diabetes mortality determined by nutrition during parents' and grandparents' slow growth period
By G. Kaati, L. Bygren, S. Edvinsson. European Journal of Human Genetics, 2002
866 citations recorded by the source corpus.
Subfields: Endocrinology, Diabetes and Metabolism, Pediatrics, Perinatology and Child Health, Physiology
View Paper: https://www.semanticscholar.org/paper/1bfbafdbdbd5a0709b2a34a8d489213a065ab621
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Endocrinology, Diabetes and Metabolism
In Pediatrics, Perinatology and Child Health
- Mark A. Hanson
- Peter D. Gluckman
- Alan Beedle
- Alexander Meissner
- T. Bale
- Barry M. Popkin
- J. Seckl
- P. Ellison
In Physiology
Citations in the corpus
- Early life events and their consequences for later disease: A life history and evolutionary perspective (2007, background): “…transmission across generations (Chong and Whitelaw, 2004; Drake and Walker, 2004), although the mechanisms and their relevance American Journal of Human Biology DOI 10.1002/ajhb to reported transgenerational inheritance in humans (Kaati et al., 2002; Pembrey et al., 2006) are poorly understood.”
- Paternal stress exposure alters sperm microRNA content and reprograms offspring HPA stress axis regulation (2013, background): “As epidemiological studies suggest that the greatest effects on offspring and grand-offspring health occur during developmental windows of increased germ cell vulnerability, we exposed males to stress either throughout puberty or only in adulthood (Kaati et al., 2002, 2007; Pembrey et al., 2006).”
- Paternally-induced transgenerational environmental reprogramming of metabolic gene expression in mammals (2010, background): “Furthermore, epidemiological data from human populations link experience of famine in paternal grandfathers to obesity and cardiovascular disease two generations later (Kaati et al., 2002; Pembrey et al., 2006).”
- Applying the Bradford Hill criteria in the 21st century: how data integration has changed causal inference in molecular epidemiology (2015, background): “For example, multiple animal studies provide support for the hypothesis that epigenetic changes induced by DES exposure in utero may be causative of transgenerational effects of DES exposure in females [32, 51–54].”