The Roles of Vitamin C in Skin Health
By J. Pullar, A. Carr, M. Vissers. Nutrients, 2017
631 citations recorded by the source corpus.
The primary function of the skin is to act as a barrier against insults from the environment, and its unique structure reflects this. The skin is composed of two layers: the epidermal outer layer is highly cellular and provides the barrier function, and the inner dermal layer ensures strength and elasticity and gives nutritional support to the epidermis. Normal skin contains high concentrations of vitamin C, which supports important and well-known functions, stimulating collagen synthesis and assisting in antioxidant protection against UV-induced photodamage. This knowledge is often used as a rationale for the addition of vitamin C to topical applications, but the efficacy of such treatment, as opposed to optimising dietary vitamin C intake, is poorly understood. This review discusses the potential roles for vitamin C in skin health and summarises the in vitro and in vivo research to date. We compare the efficacy of nutritional intake of vitamin C versus topical application, identify the areas where lack of evidence limits our understanding of the potential benefits of vitamin C on skin health, and suggest which skin properties are most likely to benefit from improved nutritional vitamin C intake.
Subfields: Biochemistry, Dermatology, Nutrition and Dietetics
View Paper: https://www.semanticscholar.org/paper/1bb895edfa33f893219eb5e60fdb38a51f97ea3d
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In Biochemistry
In Nutrition and Dietetics
Citations in the corpus
- A Review of Micronutrients and the Immune System–Working in Harmony to Reduce the Risk of Infection (2020, background): “Vitamin C is necessary for promotion of collagen synthesis in epithelial tissue [76].”
- Vitamin C and Immune Function (2017, background): “The epidermal layer is highly cellular, comprising primarily keratinocytes, whilst the dermal layer comprises fibroblasts which secrete collagen fibers, the major component of the dermis [23].”