Pulmonary toxicity of single-wall carbon nanotubes in mice 7 and 90 days after intratracheal instillation.

By C. Lam, J. James, Richard McCluskey, R. Hunter. Toxicological Sciences, 2003

2,019 citations recorded by the source corpus.

Subfields: Health, Toxicology and Mutagenesis, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/1b27b85c855d47b5e6574e3dbbc172c9140f444b

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In Health, Toxicology and Mutagenesis

In Materials Chemistry

Citations in the corpus

Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy (2005, background): “In addition, they cause inflammation in the lung upon instillation [26,33,47-49].”
Nanoparticles as drug delivery systems (2012, neutral): “[80, 101].”
Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. (2003, methodology): “Lam et al. (2003) investigated the pulmonary toxicity of three nanotube (NT) products in mice, using intratracheal instillation as the method of exposure.”
Carbon Nanotubes in Biology and Medicine: In vitro and in vivo Detection, Imaging and Drug Delivery (2009, background): “reactions due to the aggregation of hydrophobic raw CNTs in the lung airways [39, 40, 110, 111].”
The ecotoxicology and chemistry of manufactured nanoparticles (2008, background): “5 mg CNT showed 56% mortality within 7 days of exposure; macrophage granulomas formed beneath the bronchial epithelium, along with necrosis and inflammation of interstitial and peribronchial tissues during the 90-day post-exposure follow-up (Lam et al. 2004).”
The ecotoxicology of nanoparticles and nanomaterials: current status, knowledge gaps, challenges, and future needs (2008, background): “These mammalian reports have focused on respiratory toxicology and inflammation reactions to NP exposure (e.g., Oberdörster et al. 1992; Burmudez et al. 2004; Lam et al. 2004).”
Nanotechnology and Water Treatment: Applications and Emerging Opportunities (2008, methodology): “Lam et al. (2004) SWCNT 2-mg implant; Subcutaneous implantation Mice Activation of the histocompatibility complex in CD4+/CD8+ T-cells.”
Bioavailability of Nickel in Single‐Wall Carbon Nanotubes (2007, background): “The early toxicology literature includes nickle effects in SWNT by Lam et al, nickel nanoparticles and mostly nickel compounds such as nickel subsulfide (Lam et al. 2004; Zhang et al. 1998; Costa et al. 2005).”
Mechanistic investigation into antibacterial behaviour of suspensions of ZnO nanoparticles against E. coli (2010, background): “Recent reports on possible environmental and health effects of nanoparticles have raised concerns about the toxicity of nanomaterials as a critical factor for the evaluation of their applications (Donaldson and Tran 2004; Dreher 2004; Lam et al. 2004; Warheit et al. 2004; Brayner et al. 2006).”