Guidelines for the next 10 years of proteomics
By M. Wilkins, R. Appel, J. V. Van Eyk, Maxey C M Chung, A. Görg, Michael Hecker, L. Huber, H. Langen, A. Link, Y. Paik and 6 more. Proteomics, 2009
319 citations recorded by the source corpus.
In the last ten years, the field of proteomics has expanded at a rapid rate. A range of exciting new technology has been developed and enthusiastically applied to an enormous variety of biological questions. However, the degree of stringency required in proteomic data generation and analysis appears to have been underestimated. As a result, there are likely to be numerous published findings that are of questionable quality, requiring further confirmation and/or validation. This manuscript outlines a number of key issues in proteomic research, including those associated with experimental design, differential display and biomarker discovery, protein identification and analytical incompleteness. In an effort to set a standard that reflects current thinking on the necessary and desirable characteristics of publishable manuscripts in the field, a minimal set of guidelines for proteomics research is then described. These guidelines will serve as a set of criteria which editors of PROTEOMICS will use for assessment of future submissions to the Journal.
Subfields: Cell Biology, Molecular Biology, Spectroscopy
View Paper: https://www.semanticscholar.org/paper/1ae856dc44cb423624a5cd25f8dab92b86aa4fe2
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cell Biology
In Molecular Biology
In Spectroscopy
Citations in the corpus
- Historical perspective of peptidomics (2014, background): “Another aspect is the trend that for most proteomic studies, proteins identified with only a single tryptic (or other proteolytic) fragment are considered too questionable and are therefore rejected [40].”
- Scaffold: A bioinformatic tool for validating MS/MS‐based proteomic studies (2010, result): “Since then it has been discussed in several previous works [14, 21–24] and its importance is underlined in publication guidelines for several major proteomic journals [25–27].”