The evolutionary consequences of polyploidy.

By Sarah P. Otto. Cell, 2007

1,109 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/1a9f59af76b0461c2087318f42258c22387646e6

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Citations in the corpus

Next-Generation Sequencing — An Overview of the History, Tools, and “Omic” Applications (2016, methodology): “NGS has been used to diagnose rare Mendelian diseases and genetically heterogeneous complex disorders, such as X-linked intellectual disability, congenital disorders, cancer genome heterogeneity, and fetal aneuploi‐ dy [13, 15, 123, 125, 208, 209, 274, 275].”
polysat: an R package for polyploid microsatellite analysis (2011, background): “Given that an estimated 35% of plant species (Wood et al. 2009) and at least 200 animal species (Otto 2007) are of recent polyploid origin, we expect our software to be widely useful in population and ecological genetic research.”
Influence of phylogeny and ploidy on species ranges of North American angiosperms (2009, background): “Indeed, since all angiosperms are estimated to have paleopolyploid origins, all plants included in this study likely have experienced multiple rounds of polyploidization in their evolutionary histories (Otto & Whitton 2000; Otto 2007).”
Is post-polyploidization diploidization the key to the evolutionary success of angiosperms? (2016, background): “This depends on the dominance of new beneficial mutations versus the pre-existing allele; therefore, if it is at least partially recessive it will be masked, resulting in inefficient selection (Stebbins, 1971; Otto, 2007), and leading to the idea that polyploids are ‘evolutionary dead-ends’ (Stebbin”
The more the better? The role of polyploidy in facilitating plant invasions. (2012, neutral): “Otto SP. 2007.”
The “Polyploid Hop”: Shifting Challenges and Opportunities Over the Evolutionary Lifespan of Genome Duplications (2018, background): “…mis-segregation to altered gene expression, changes in cell size or in intracellular physiology (Ramsey and Schemske, 2002; Osborn et al., 2003; Adams and Wendel, 2005; Comai, 2005; Chen and Ni, 2006; Chen, 2007; Otto, 2007; Parisod et al., 2010; Brownfield and Köhler, 2011; Hollister, 2015).”
Mitotic chromosome doubling of plant tissues in vitro (2010, background): “Examples are loss of duplicated genes, gene expression alterations and epigenetic changes modulating gene expression as reviewed by Osborn et al. (2003), Otto (2007) and Parisod et al. (2010).”
Plants with double genomes might have had a better chance to survive the Cretaceous–Tertiary extinction event (2009, result): “The relatively low incidence of paleopolyploidy over the last 110 my compared to present-day rates of polyploid formation and the fact that a considerable fraction of the polyploids that survived seem to be clustered in time, might be explained by the fact that polyploidy is usually an evolutionary ”
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes (2020, background): “More generally, poly-ploidization events have important consequences to genome evolution 9,10 .”
Evolution of Genome Size in Duckweeds (Lemnaceae) (2011, background): “Changes in genome structure could lead to differential gene loss, extensive changes in gene expression [27], and have immediate effects on the phenotype and fitness of an individual [28].”