Hypervirulent Klebsiella pneumoniae

By P. Patel, T. Russo, A. Karchmer. Open Forum Infectious Diseases, 2014

619 citations recorded by the source corpus.

Hypervirulent strains of Klebsiella pneumoniae are associated with abscess formation, commonly hepatic, and metastatic spread, even in healthy patients. We describe a case of this clinical syndrome, genotypic and phenotypic features of the isolate, and briefly review epidemiology, clinical manifestations, and pathogenesis of this underappreciated syndrome.

Subfields: Infectious Diseases, Molecular Medicine, Parasitology

View Paper: https://www.semanticscholar.org/paper/1a048b9f27b50cadd11779c2a2f0dd9d061f8705

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In Molecular Medicine

1. J. Mecsas
2. M. Paczosa

Citations in the corpus

• Klebsiella pneumoniae: Going on the Offense with a Strong Defense (2016, background): “pneumoniae diseases has been observed clinically (37, 38).”
• Identification of Biomarkers for Differentiation of Hypervirulent Klebsiella pneumoniae from Classical K. pneumoniae (2018, background): “Specifically, accurate identification of hvKp would allow more rapid consideration of possible unrecognized sites of infection, which often manifest as occult abscesses (37).”