Extracellular vesicles from blood plasma: determination of their morphology, size, phenotype and concentration

By N. Arraud, Romain Linares, Sisareuth Tan, C. Gounou, J. Pasquet, S. Mornet, A. Brisson. Journal of Thrombosis and Haemostasis, 2014

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Biological properties of extracellular vesicles and their physiological functions (2015, result): “Although plasma-derived EVs are a mixture of vesicles from the cells lining the blood vessels and the different cells found in blood, the largest individual population of EVs in plasma is positive for platelet specific markers (such as, CD41a, CD61 andGPIb) and are considered now to be 25% of the to”
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation. (2014, background): “We thus foresee that these tubular structures might also express mitochondria.(59,60) Keeping in mind that platelets rapidly respond to vascular injuries to prevent bleeding and that mitochondria might also be released in this context, we further speculate that extracellular mitochondria could contr”