Polyspecific Organic Cation Transporters: Structure, Function, Physiological Roles, and Biopharmaceutical Implications

By H. Koepsell, K. Lips, C. Volk. Pharmaceutical Research, 2007

997 citations recorded by the source corpus.

Subfields: Biochemistry, Oncology, Organic Chemistry

View Paper: https://www.semanticscholar.org/paper/198a9bf73eb8a2da284f790d2491658473ed0794

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. M. Roth
2. A. Obaidat
3. B. Hagenbuch
4. J. L. Boyer

In Oncology

1. M. Roth
2. A. Obaidat
3. Christoph Borner
4. B. Hagenbuch
5. J. L. Boyer

In Organic Chemistry

1. N. Cameron

Citations in the corpus

• Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME (2013, positive): “OCT1 (SLC22A1) is expressed at high level, and OCT3 (SLC22A3) is expressed at lower levels in the basolateral membrane of hepatocytes (Koepsell et al. 2007).”
• OATPs, OATs and OCTs: the organic anion and cation transporters of the SLCO and SLC22A gene superfamilies (2012, background): “OCTN2 also mediates both sodiumdependent and sodium-independent uptake, depending on the substrate (Koepsell et al., 2007).”
• Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation (2010, neutral): “5 mM (Koepsell et al., 2007).”