The IgG Fc Contains Distinct Fc Receptor (FcR) Binding Sites: The Leukocyte Receptors FcγRI and FcγRIIa Bind to a Region in the Fc Distinct from That Recognized by Neonatal FcR and Protein A1

By B. Wines, M. Powell, P. Parren, N. Barnes, P. Hogarth. Journal of Immunology, 2000

144 citations recorded by the source corpus.

Subfields: Immunology and Allergy, Molecular Biology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/194fd82f85b84f526fee46a273c4fb670b70ca98

Citations in the corpus

• Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein (2021, unknown): “To test this hypothesis, we engineered LALA-PG mutations into the Fc region of these human IgG1 mAbs to abrogate interaction of the Fc region with FcgRs and complement proteins (Lund et al., 1991; Wines et al., 2000).”