The natural history of compensated cirrhosis due to hepatitis C virus: A 17‐year cohort study of 214 patients

By A. Sangiovanni, G. Prati, P. Fasani, G. Ronchi, R. Romeo, M. Manini, E. Del Ninno, A. Morabito, M. Colombo. Hepatology, 2006

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Hepatitis C Guidance 2019 Update: AASLD-IDSA Recommendations for Testing, Managing, and Treating Hepatitis C Virus Infection (2019, background): “Ongoing imaging surveillance for HCC and gastroesophageal varices is recommended for patients with cirrhosis.(78-80) Cirrhosis with portal hypertension portends a greater likelihood of developing future hepatic complications in untreated patients.”
EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. (2012, background): “Overall, one-third of cirrhotic patients will develop HCC during their lifetime [10].”
EASL Clinical Practice Guidelines: Management of hepatocellular carcinoma. (2018, background): “Overall, one-third of cirrhotic patients will develop HCC during their lifetime.(15) Long-term follow-up studies have found that approximately 1–8% of patients with cirrhosis develop HCC per year (e.”
Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update (2017, background): “5% per year would require implementing a surveillance strategy in patients with cirrhosis [395], which would be irrespective of the etiology involved [396, 397].”
EASL-EORTC clinical practice guidelines: management of hepatocellular carcinoma. (2012, background): “Overall, one-third of cirrhotic patients will develop HCC during their lifetime [10].”