Role of human DNA polymerase κ as an extender in translesion synthesis

By L. Haracska, L. Prakash, S. Prakash. Proceedings of the National Academy of Sciences of the United States of America, 2002

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Efficient and Error-Free Replication Past a Minor-Groove DNA Adduct by the Sequential Action of Human DNA Polymerases ι and κ (2004, background): “A role for Pol in the extension step has been suggested from its ability to proficiently extend from nucleotides opposite the 3 To f aT T dimer or from nucleotides incorporated opposite an O6-methylguanine; Pol, however, is very inefficient at incorporating nucleotides opposite both these DNA lesion”
Mechanisms of human DNA repair: an update. (2003, background): “…et al., 2000b Pol kappa (Pol␬) AP-sites and (AAF)-adducts Ohashi et al., 2000b A opposite thymine-glycol Fischhaber et al., 2002 A opposite 8-OxoG Haracska et al., 2002 A opposite AP-sites and 8-OxoG Kusumoto et al., 2002 Pol iota (Pol␫) T or G opposite the 3 T of the CPD Tissier et al., 2000a…”