3D tumor spheroids: an overview on the tools and techniques used for their analysis.
By Elisabete C. Costa, A. Moreira, D. de Melo-Diogo, V. Gaspar, Marco P Carvalho, I. Correia. Biotechnology Advances, 2016
782 citations recorded by the source corpus.
Subfields: Biomedical Engineering, Cell Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/18bc0ffe7e6634c2337b0a4949bbb35d4f4ce46a
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In Oncology
Citations in the corpus
- 3D tumor spheroids as in vitro models to mimic in vivo human solid tumors resistance to therapeutic drugs (2018, background): “…(a) cell seeding on an acellular 3D artificial matrix (e.g., inserts, membranes, and sponges) and (b) dispersion of cells in a hydrogel often followed by its ionic cross‐ linking or radical polymerization (Carvalho, Costa, Miguel, & Correia, 2016; Y. Fang & Eglen, 2017; Knight & Przyborski, 2015).”
- Targeting Tumor Microenvironment for Cancer Therapy (2019, background): “, survival, proliferation, gene expression heterogeneity and multidrug resistance), also enabling the control of environmental factors and measurement of cell responses [184,185].”