Vascular risk factors for Alzheimer's disease: an epidemiologic perspective.

By Monique M. B. Breteler. Neurobiology of Aging, 2000

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Aggregation of vascular risk factors and risk of incident Alzheimer disease (2005, background): “Explanations for these associations include the coincidence of common disorders in the elderly, vascular and cerebrovascular disease precipitating AD, an additive or synergistic (AD + vascular) pathogenesis of dementia, or misclassification of vascular dementia as AD (16).”
Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases (2013, positive): “The merit of this 2001 report is that it was one of the first to point out that the metabolites of flavonoids, rather than their parent compounds, may contribute to the epidemiologically reported effects of flavonoids in terms of reducing the risk of CVD.”
Vascular Contributions to Cognitive Impairment and Dementia Including Alzheimer’s Disease (2014, background): “Decades of data, including landmark work of the Honolulu Asia Aging Study (HAAS), the Rotterdam Study (20), and the Religious Orders Study and Memory and Aging Project (ROS/MAP) (12, 13) have provided significant insight into potential links of vascular factors to dementia, such as AD.”
Age-Associated Reductions in Cerebral Blood Flow Are Independent from Regional Atrophy (2010, background): “A number of epidemiological (Aguero-Torres et al., 2006; Breteler, 2000; Ruitenberg et al., 2005), pharmacotherapeutic (Duron and Hanon, 2010; Forette et al.”