Anxiolytic effects of nicotine in zebrafish.

By E. Levin, Zachary Bencan, D. Cerutti. Physiology and Behavior, 2007

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Video-Aided Analysis of Zebrafish Locomotion and Anxiety-Related Behavioral Responses (2011, background): “with higher levels of anxiety elicited by different stressors [3, 8, 10] (Table 1).”
Understanding behavioral and physiological phenotypes of stress and anxiety in zebrafish (2009, background): “Several studies have already examined anxiety in zebrafish using anxiolytic agents such as nicotine [31], -fluromethylhistidine [35], ethanol [6] and diazepam [36].”
A comparison of the light/dark and novel tank tests in zebrafish (2012, methodology): “When placed in a novel tank, zebrafish initially exhibit pronounced behavioral inhibition (remaining near the bottom of the tank with limited locomotor/exploratory activity), which gradually habituates with prolonged exposure (Levin et al., 2007; Cachat et al., 2010, 2011a; Wong et al., 2010; Rosemb”