SNPStats: a web tool for the analysis of association studies

By X. Solé, E. Guinó, Joan Valls, R. Iniesta, Víctor Moreno. Bioinform., 2006

1,069 citations recorded by the source corpus.

SUMMARY A web-based application has been designed from a genetic epidemiology point of view to analyze association studies. Main capabilities include descriptive analysis, test for Hardy-Weinberg equilibrium and linkage disequilibrium. Analysis of association is based on linear or logistic regression according to the response variable (quantitative or binary disease status, respectively). Analysis of single SNPs: multiple inheritance models (co-dominant, dominant, recessive, over-dominant and log-additive), and analysis of interactions (gene-gene or gene-environment). Analysis of multiple SNPs: haplotype frequency estimation, analysis of association of haplotypes with the response, including analysis of interactions. AVAILABILITY http://bioinfo.iconcologia.net/SNPstats. Source code for local installation is available under GNU license.

Subfields: Genetics

View Paper: https://www.semanticscholar.org/paper/17c493253c50e1cdba8b5cca7df8b0cf361d5847

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