miRWalk: An online resource for prediction of microRNA binding sites

By C. Sticht, C. de la Torre, Alisha Parveen, N. Gretz. PLoS ONE, 2018

1,478 citations recorded by the source corpus.

miRWalk is an open-source platform providing an intuitive interface that generates predicted and validated miRNA-binding sites of known genes of human, mouse, rat, dog and cow. The core of miRWalk is the miRNA target site prediction with the random-forest-based approach software TarPmiR searching the complete transcript sequence including the 5’-UTR, CDS and 3’-UTR. Moreover, it integrates results other databases with predicted and validated miRNA-target interactions. The focus is set on a modular design and extensibility as well as a fast update cycle. The database is available using Python, MySQL and HTML/Javascript Database URL: http://mirwalk.umm.uni-heidelberg.de.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/169911235047cd04e5173f2a75617b534a7ea1dd