Nitric oxide, stomatal closure, and abiotic stress.

By S. Neill, R. Barros, J. Bright, Radhika Desikan, J. Hancock, J. Harrison, P. Morris, D. Ribeiro, I. Wilson. Journal of Experimental Botany, 2007

742 citations recorded by the source corpus.

Various data indicate that nitric oxide (NO) is an endogenous signal in plants that mediates responses to several stimuli. Experimental evidence in support of such signalling roles for NO has been obtained via the application of NO, usually in the form of NO donors, via the measurement of endogenous NO, and through the manipulation of endogenous NO content by chemical and genetic means. Stomatal closure, initiated by abscisic acid (ABA), is effected through a complex symphony of intracellular signalling in which NO appears to be one component. Exogenous NO induces stomatal closure, ABA triggers NO generation, removal of NO by scavengers inhibits stomatal closure in response to ABA, and ABA-induced stomatal closure is reduced in mutants that are impaired in NO generation. The data indicate that ABA-induced guard cell NO generation requires both nitric oxide synthase-like activity and, in Arabidopsis, the NIA1 isoform of nitrate reductase (NR). NO stimulates mitogen-activated protein kinase (MAPK) activity and cGMP production. Both these NO-stimulated events are required for ABA-induced stomatal closure. ABA also stimulates the generation of H2O2 in guard cells, and pharmacological and genetic data demonstrate that NO accumulation in these cells is dependent on such production. Recent data have extended this model to maize mesophyll cells where the induction of antioxidant defences by water stress and ABA required the generation of H2O2 and NO and the activation of a MAPK. Published data suggest that drought and salinity induce NO generation which activates cellular processes that afford some protection against the oxidative stress associated with these conditions. Exogenous NO can also protect cells against oxidative stress. Thus, the data suggest an emerging model of stress responses in which ABA has several ameliorative functions. These include the rapid induction of stomatal closure to reduce transpirational water loss and the activation of antioxidant defences to combat oxidative stress. These are two processes that both involve NO as a key signalling intermediate.

Subfields: Plant Science

View Paper: https://www.semanticscholar.org/paper/1683a5335e4c7e45f38f71416e927dea85cefa9c

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Citations in the corpus

Guard Cell Signal Transduction Network: Advances in Understanding Abscisic Acid, CO2, and Ca2+ Signaling (2010, background): “The roles of nitric oxide and reactive oxygen species in ABA signaling and components of this signaling pathway have been recently reviewed (129).”
Hydrogen peroxide and nitric oxide mediate K+/Na+ homeostasis and antioxidant defense in NaCl-stressed callus cells of two contrasting poplars (2010, background): “Like H2O2, NO—produced by nitric oxide synthase (NOS), is suggested to play a crucial role in ionic homeostasis and antioxidant defense (Zhao et al. 2004, 2007; Zhang et al. 2007; Qiao and Fan 2008; Neill et al. 2008; Qiao et al. 2009).”
A review of soil NO transformation: associated processes and possible physiological significance on organisms (2015, background): “…in stomatal 1418 regulation (Garcı́a-Mata and Lamattina, 2001; Desikan et al., 2002; Neill et 1419 al., 2002), root nitrogen uptake and metabolism (Simon et al., 2009; 2013) 1420 and adaptive responses to abiotic stress (Neill et al., 2003; 2008; Besson-1421 Bard et al., 2008; Mur et al., 2012).”
cGMP signalling in plants: from enigma to main stream. (2018, background): “cGMP content of pea epidermis and Arabidopsis guard cell fragments transiently increases following ABA treatment and (Neill et al. 2008) while the same investigators (Neill et al.”
Polyamines: molecules with regulatory functions in plant abiotic stress tolerance (2010, background): “Both H2O2 and NO are involved in the regulation of stomatal movements in response to ABA, in such a way that NO generation depends on H2O2 production (Neill et al. 2008).”