Secondary metabolism of hairy root cultures in bioreactors

By Yoojeong Kim, B. Wyslouzil, P. Weathers. In vitro cellular & developmental biology. Plant, 2007

274 citations recorded by the source corpus.

Subfields: Biotechnology, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/159599cf72e299e49c99e9371fce109843b37252

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In Biotechnology

1. C. Taylor
2. Sheela Chandra
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4. R. Chandra

In Molecular Biology

1. V. Georgiev
2. A. Pavlov
3. Ivan Georgiev Ivanov
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In Plant Science

1. V. Georgiev
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4. Thomas Bley
5. C. Taylor
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Citations in the corpus

• Design of bioreactors suitable for plant cell and tissue cultures (2008, background): “Immobilization of hairy roots by horizontal or vertical meshes as well as by cages or polyurethane foam demonstrably promotes their growth in submerged stirred bioreactors, bubble columns, airlift reactors and drum reactors, where the roots are immersed in the culture medium (Eibl and Eibl 2002; Ki”
• Production of asiaticoside and madecassoside in Centella asiatica in vitro and in vivo (2007, background): “Plant secondary metabolites are normally synthesised by specialised cells, often at distinct stages of plant development, and certain compounds are not synthesised if cells remain undifferentiated (Kim et al. 2002).”
• Agrobacterium rhizogenes: recent developments and promising applications (2007, background): “Hairy root cultures are usually able to produce the same compounds found in wild-type roots of the parent plant, without the loss of concentration frequently observed with callus or cell suspension cultures (Kim et al. 2002a, b).”
• Improvement of atropine production by different biotic and abiotic elicitors in hairy root cultures of Datura metel (2015, background): “Introduction Plant-derived drugs are important sources of various pharmaceuticals (Kim et al., 2002).”
• Engineering secondary metabolite production in hairy roots (2011, background): “Excellent reviews are available on hairy root culture by a group of workers in the last few decades (Toivonen 1993, Shanks and Morgan 1999, Giri and Narasu 2000, Kino-oka et al. 2001, Kim et al. 2002, Eibl and Eibl 2008, Mishra and Ranjan 2008).”
• Bioprocessing of differentiated plant in vitro systems (2013, methodology): “Thus they offer the advantage of improved oxygen and nutrient availability, better gas exchange and reduced shear stress [4,5,27].”