Leisure-Time Running Reduces All-Cause and Cardiovascular Mortality Risk
By Duck-chul Lee, R. Pate, C. Lavie, Xuemei Sui, T. Church, S. Blair. Journal of the American College of Cardiology, 2014
789 citations recorded by the source corpus.
Background Although running is a popular leisure-time physical activity, little is known about the long-term effects of running on mortality. The dose-response relations between running, as well as the change in running behaviors over time and mortality remain uncertain. Objectives We examined the associations of running with all-cause and cardiovascular mortality risks in 55,137 adults, aged 18 to 100 years (mean age, 44). Methods Running was assessed on the medical history questionnaire by leisure-time activity. Results During a mean follow-up of 15 years, 3,413 all-cause and 1,217 cardiovascular deaths occurred. Approximately, 24% of adults participated in running in this population. Compared with non-runners, runners had 30% and 45% lower adjusted risks of all-cause and cardiovascular mortality, respectively, with a 3-year life expectancy benefit. In dose-response analyses, the mortality benefits in runners were similar across quintiles of running time, distance, frequency, amount, and speed, compared with non-runners. Weekly running even <51 minutes, <6 miles, 1-2 times, <506 metabolic equivalent-minutes, or <6 mph was sufficient to reduce risk of mortality, compared with not running. In the analyses of change in running behaviors and mortality, persistent runners had the most significant benefits with 29% and 50% lower risks of all-cause and cardiovascular mortality, respectively, compared with never-runners. Conclusions Running, even 5-10 minutes per day and slow speeds <6 mph, is associated with markedly reduced risks of death from all causes and cardiovascular disease. This study may motivate healthy but sedentary individuals to begin and continue running for substantial and attainable mortality benefits.
Subfields: Cardiology and Cardiovascular Medicine, Complementary and alternative medicine, Physiology
View Paper: https://www.semanticscholar.org/paper/1581c83d24df622bb6a6982ad1eee355a093c6f5
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Cardiology and Cardiovascular Medicine
In Complementary and alternative medicine
In Physiology
Citations in the corpus
- Pediatric Obesity-Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline. (2017, positive): “Recent studies in Denmark and elsewhere have demonstrated benefits in mild intensity jogging and in small 10-to 15-minute intervals of exercise, which may be more readily achievable (219, 220).”
- 2016 European Guidelines on cardiovascular disease prevention in clinical practice (2017, positive): “1 Aerobic physical activity Aerobic PA, the most studied and recommended modality, with a beneficial dose– response effect on prognosis [259, 260, 268], consists of movements of large muscle mass in a rhythmic manner for a sustained period.”
- Physical activity: Health impact, prevalence, correlates and interventions (2017, background): “recent systematic reviews/meta-analyses of the literature (Arem et al., 2015; Lee et al., 2014; Löllgen, Böckenhoff, & Knapp, 2009; Paterson & Warburton, 2010; Warburton et al., 2010; Wen et al., 2011) have revealed marked risk reductions with relatively small volumes of PA.”
- Physical activity and cardiorespiratory fitness as major markers of cardiovascular risk: their independent and interwoven importance to health status. (2015, background): “In this regard, a recent study found markedly lower mortality risk in those who jog slowly as little as 5-10 minutes per day (32).”