Mn, Fe, and Co-Catalyzed Radical Hydrofunctionalizations of Olefins

By Steven W. M. Crossley, C. Obradors, R. M. Martínez, R. Shenvi. Chemical Reviews, 2016

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Cofactor-mimetic aerobic oxidation has conceptually merged with catalysis of syngas reactions to form a wide range of Markovnikov-selective olefin radical hydrofunctionalizations. We cover the development of the field and review contributions to reaction invention, mechanism and application to complex molecule synthesis. We also provide a mechanistic framework for understanding this compendium of radical reactions.

Subfields: Organic Chemistry, Renewable Energy, Sustainability and the Environment

View Paper: https://www.semanticscholar.org/paper/157db6b023dd01587396ad1152973c04eec6db61