Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites

By S. Ōmura, H. Ikeda, J. Ishikawa, Akiharu Hanamoto, C. Takahashi, M. Shinose, Yōko Takahashi, H. Horikawa, H. Nakazawa, Tomomi Osonoe and 4 more. Proceedings of the National Academy of Sciences of the United States of America, 2001

819 citations recorded by the source corpus.

Subfields: Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/153a683b4a66699599463df6152f0455097e36c5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. T. Stein
2. Rainer Borriss
3. J. Peralta‐Sánchez
4. A. Møller
5. Alemu Nega

In Pharmacology

1. T. Stein
2. Alemu Nega

Citations in the corpus

• Number and colour composition of nest lining feathers predict eggshell bacterial community in barn swallow nests: an experimental study (2010, background): “Most bacteria detected on feathers belong to the genera Enterococcus, Staphylococcus (Parisien et al. 2008), Streptomyces (Omura et al. 2001) and Bacillus (Burtt & Ichida 1999; Gunderson 2008).”
• Bacillus subtilis antibiotics: structures, syntheses and specific functions (2005, background): “…antibiotic syntheses is comparable with Bacillus amyloliquefaciens (six operons of 306 kb, 7.5% of the genome; Koumoutsi et al., 2004) but stays behind the potential of Streptomycetes such as Streptomycetes avermitilis (25 operons of 560 kb corresponding to 6.4% of the genome; Omura et al., 2001).”
• Structural and Functional Characterization of Gene Clusters Directing Nonribosomal Synthesis of Bioactive Cyclic Lipopeptides in Bacillus amyloliquefaciens Strain FZB42 (2004, background): “4% of the entire genome is devoted to the production of secondary metabolites (27).”