Microbial translocation is a cause of systemic immune activation in chronic HIV infection

By J. Brenchley, D. Price, T. Schacker, Tedi E. Asher, G. Silvestri, S. Rao, Zachary Kazzaz, E. Bornstein, O. Lambotte, D. Altmann and 10 more. Nature Medicine, 2006

1,508 citations recorded by the source corpus.

Subfields: Immunology, Virology

View Paper: https://www.semanticscholar.org/paper/150b07aa855da5a874315e76fdab62e30f6883f5

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. Daniel C. Douek
2. Steven G. Deeks
3. J. Snyder-Cappione
4. Anna C. Belkina
5. Herbert W. Virgin
6. Mario Roederer

In Virology

1. Daniel C. Douek
2. Steven G. Deeks
3. S. Lewin

Citations in the corpus

• Plasma levels of soluble CD14 independently predict mortality in HIV infection. (2011, methodology): “Although markers of microbial translocation have been associated with immune activation in HIV disease, the clinical significance of these relationships is poorly defined [17, 27].”
• Virus-Plus-Susceptibility Gene Interaction Determines Crohn’s Disease Gene Atg16L1 Phenotypes in Intestine (2010, background): “There is also evidence for an intersection between viral infection and commensal bacteria (Brenchley et al., 2006; Xi et al., 2008).”
• Multivariate Computational Analysis of Gamma Delta T Cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging (2018, background): “The integrity of the gastrointestinal epithelial barrier is compromised in HIV and SIV infection (79, 83) and does not sufficiently recover with effective ART (84).”