Nomenclature update for the mammalian UDP glycosyltransferase (UGT) gene superfamily.

By P. Mackenzie, K. Bock, B. Burchell, C. Guillemette, S. Ikushiro, T. Iyanagi, J. Miners, I. Owens, D. Nebert. Pharmacogenetics & Genomics, 2005

878 citations recorded by the source corpus.

Subfields: Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/14a0478668814989cdd150e1f5b32372ad1b32ed

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1. A. Rowland
2. J. Miners
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Citations in the corpus

• The UDP-glucuronosyltransferases: their role in drug metabolism and detoxification. (2013, background): “At an volutionary level, the human UGTs are related to enzyme famlies in bacteria, yeast and plants, that catalyse the transfer of a lycosyl group from a nucleotide sugar (i.e. UDPGlc, UDP-galactose r UDPXyl) to a lipophilic substrate (Mackenzie et al., 2005).”
• METABOLISM AND DISPOSITION OF ACETAMINOPHEN: RECENT ADVANCES IN RELATION TO HEPATOTOXICITY AND DIAGNOSIS (2013, neutral): “been described in humans and rodents, belonging to four families (UGT1, UGT2, UGT3, and UGT8) (46).”