Structure and function of the human insula

By Lucina Q. Uddin, Jason S. Nomi, Benjamin Hébert-Seropian, Jimmy Ghaziri, O. Boucher. Journal of clinical neurophysiology, 2017

1,033 citations recorded by the source corpus.

The insular cortex, or “Island of Reil”, is hidden deep within the lateral sulcus of the brain. Subdivisions within the insula have been identified on the basis of cytoarchitectonics, sulcal landmarks, and connectivity. Depending on the parcellation technique employed, the insula can be divided into anywhere between 2 and 13 distinct subdivisions. The insula subserves a wide variety of functions in humans ranging from sensory and affective processing to high-level cognition. Here we provide a concise summary of known structural and functional features of the human insular cortex with a focus on lesion case studies and recent neuroimaging evidence for considerable functional heterogeneity of this brain region.

Subfields: Cognitive Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/1434c634b5fdd87d8e03a123b6f261509238073d

Citations in the corpus

• Decision and response monitoring during working memory are sequentially represented in the human insula (2022, unknown): “INTRODUCTION Interest in the human insula has increased commensurate with the development of improved methods to study this structure.(1,2) The insula is located deep within the lateral sulcus of the brain.”